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SLC41A3 has not been detected as a mutational cancer driver

SLC41A3
Ensembl id ENSG00000114544
Mutated samples
Coding Sequence 47 (0.7%)
Protein Affecting 19 (0.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all SLC41A3 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Uterine corpus endometrioid carcinoma No 5 4 1.74
Breast carcinoma No 6 3 0.26
Cutaneous melanoma No 12 3 0.81
Head and neck squamous cell carcinoma No 3 3 0.80
Bladder carcinoma No 3 2 2.04
Renal clear cell carcinoma No 2 1 0.24
Thyroid carcinoma No 2 1 0.31
Neuroblastoma No 1 1 0.48
Colorectal adenocarcinoma No 3 1 0.44
Prostate adenocarcinoma No 2 0 0.00
Lung adenocarcinoma No 1 0 0.00
Hepatocarcinoma No 1 0 0.00
Lung squamous cell carcinoma No 2 0 0.00
Chronic lymphocytic leukemia No 3 0 0.00
Esophageal carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence