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SLC2A9 has not been detected as a mutational cancer driver

SLC2A9
Ensembl id ENSG00000109667
Mutated samples
Coding Sequence 166 (2.4%)
Protein Affecting 32 (0.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all SLC2A9 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 54 10 2.71
Stomach adenocarcinoma No 11 5 3.11
Lung adenocarcinoma No 17 4 1.02
Uterine corpus endometrioid carcinoma No 8 3 1.30
Prostate adenocarcinoma No 6 2 0.82
Breast carcinoma No 7 2 0.17
Lung squamous cell carcinoma No 8 2 1.15
Acute myeloid leukemia No 1 1 0.51
Thyroid carcinoma No 1 1 0.31
Small cell lung carcinoma No 3 1 1.45
Head and neck squamous cell carcinoma No 11 1 0.27
Bladder carcinoma No 3 0 0.00
Pancreas adenocarcinoma No 1 0 0.00
Renal clear cell carcinoma No 4 0 0.00
Non small cell lung carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 2 0 0.00
Multiple myeloma No 3 0 0.00
Lower grade glioma No 2 0 0.00
Serous ovarian adenocarcinoma No 3 0 0.00
Pylocytic astrocytoma No 1 0 0.00
Colorectal adenocarcinoma No 3 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
Glioblastoma multiforme No 11 0 0.00
Esophageal carcinoma No 4 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence