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SLC26A6 has not been detected as a mutational cancer driver

SLC26A6
Ensembl id ENSG00000225697
Mutated samples
Coding Sequence 71 (1.0%)
Protein Affecting 31 (0.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all SLC26A6 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 30 13 3.52
Breast carcinoma No 9 4 0.35
Lung adenocarcinoma No 8 3 0.77
Lung squamous cell carcinoma No 5 2 1.15
Stomach adenocarcinoma No 4 2 1.24
Esophageal carcinoma No 2 2 1.37
Prostate adenocarcinoma No 2 1 0.41
Bladder carcinoma No 2 1 1.02
Uterine corpus endometrioid carcinoma No 2 1 0.43
Serous ovarian adenocarcinoma No 1 1 0.32
Head and neck squamous cell carcinoma No 1 1 0.27
Hepatocarcinoma No 1 0 0.00
Thyroid carcinoma No 2 0 0.00
Neuroblastoma No 1 0 0.00
Colorectal adenocarcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence