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SLC25A53 has not been detected as a mutational cancer driver

SLC25A53
Ensembl id ENSG00000176274
Mutated samples
Coding Sequence 50 (0.7%)
Protein Affecting 23 (0.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all SLC25A53 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 18 8 2.17
Lung adenocarcinoma No 4 4 1.02
Breast carcinoma No 5 3 0.26
Lower grade glioma No 2 2 1.18
Renal clear cell carcinoma No 2 1 0.24
Multiple myeloma No 1 1 1.45
Stomach adenocarcinoma No 2 1 0.62
Small cell lung carcinoma No 2 1 1.45
Colorectal adenocarcinoma No 1 1 0.44
Head and neck squamous cell carcinoma No 2 1 0.27
Hepatocarcinoma No 1 0 0.00
Bladder carcinoma No 1 0 0.00
Uterine corpus endometrioid carcinoma No 2 0 0.00
Chronic lymphocytic leukemia No 2 0 0.00
Serous ovarian adenocarcinoma No 1 0 0.00
Pylocytic astrocytoma No 1 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
Glioblastoma multiforme No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence