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SLC25A43 has not been detected as a mutational cancer driver

SLC25A43
Ensembl id ENSG00000077713
Mutated samples
Coding Sequence 21 (0.3%)
Protein Affecting 14 (0.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all SLC25A43 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Small cell lung carcinoma No 2 2 2.90
Colorectal adenocarcinoma No 2 2 0.87
Head and neck squamous cell carcinoma No 2 2 0.53
Lung adenocarcinoma No 1 1 0.26
Bladder carcinoma No 1 1 1.02
Breast carcinoma No 1 1 0.09
Thyroid carcinoma No 1 1 0.31
Cutaneous melanoma No 3 1 0.27
Neuroblastoma No 1 1 0.48
Stomach adenocarcinoma No 1 1 0.62
Esophageal carcinoma No 1 1 0.68
Hepatocarcinoma No 1 0 0.00
Medulloblastoma No 1 0 0.00
Lung squamous cell carcinoma No 1 0 0.00
Uterine corpus endometrioid carcinoma No 1 0 0.00
Pylocytic astrocytoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence