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SLC23A3 has not been detected as a mutational cancer driver

SLC23A3
Ensembl id ENSG00000213901
Mutated samples
Coding Sequence 60 (0.9%)
Protein Affecting 25 (0.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all SLC23A3 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 17 5 1.36
Lung adenocarcinoma No 6 4 1.02
Breast carcinoma No 4 3 0.26
Bladder carcinoma No 3 2 2.04
Uterine corpus endometrioid carcinoma No 7 2 0.87
Stomach adenocarcinoma No 4 2 1.24
Head and neck squamous cell carcinoma No 3 2 0.53
Lung squamous cell carcinoma No 3 1 0.57
Renal clear cell carcinoma No 3 1 0.24
Neuroblastoma No 1 1 0.48
Lower grade glioma No 1 1 0.59
Colorectal adenocarcinoma No 3 1 0.44
Hepatocarcinoma No 1 0 0.00
Medulloblastoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Pylocytic astrocytoma No 1 0 0.00
Glioblastoma multiforme No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence