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SI has not been detected as a mutational cancer driver

SI
Ensembl id ENSG00000090402
Mutated samples
Coding Sequence 364 (5.4%)
Protein Affecting 310 (4.6%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all SI gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 91 78 21.14
Lung adenocarcinoma No 52 44 11.25
Head and neck squamous cell carcinoma No 49 41 10.93
Lung squamous cell carcinoma No 33 33 18.97
Breast carcinoma No 19 17 1.48
Small cell lung carcinoma No 14 14 20.29
Uterine corpus endometrioid carcinoma No 14 13 5.65
Stomach adenocarcinoma No 11 10 6.21
Serous ovarian adenocarcinoma No 9 9 2.85
Esophageal carcinoma No 15 9 6.16
Renal clear cell carcinoma No 6 6 1.44
Chronic lymphocytic leukemia No 13 5 1.72
Bladder carcinoma No 6 4 4.08
Neuroblastoma No 5 4 1.90
Multiple myeloma No 5 4 5.80
Lower grade glioma No 4 4 2.37
Non small cell lung carcinoma No 3 3 9.68
Colorectal adenocarcinoma No 3 3 1.31
Glioblastoma multiforme No 5 3 0.79
Acute myeloid leukemia No 2 2 1.02
Diffuse B cell lymphoma No 2 2 8.70
Hepatocarcinoma No 1 1 1.11
Pancreas adenocarcinoma No 1 1 0.47
Thyroid carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence