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SH3RF3 has not been detected as a mutational cancer driver

SH3RF3
Ensembl id ENSG00000172985
Mutated samples
Coding Sequence 39 (0.6%)
Protein Affecting 21 (0.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all SH3RF3 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 7 4 1.08
Head and neck squamous cell carcinoma No 5 4 1.07
Hepatocarcinoma No 4 3 3.33
Lung adenocarcinoma No 3 2 0.51
Uterine corpus endometrioid carcinoma No 2 2 0.87
Esophageal carcinoma No 2 2 1.37
Bladder carcinoma No 1 1 1.02
Lung squamous cell carcinoma No 1 1 0.57
Stomach adenocarcinoma No 1 1 0.62
Glioblastoma multiforme No 1 1 0.26
Breast carcinoma No 1 0 0.00
Renal clear cell carcinoma No 1 0 0.00
Thyroid carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 5 0 0.00
Serous ovarian adenocarcinoma No 2 0 0.00
Pylocytic astrocytoma No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence