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SGIP1 has not been detected as a mutational cancer driver

SGIP1
Ensembl id ENSG00000118473
Mutated samples
Coding Sequence 105 (1.5%)
Protein Affecting 82 (1.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all SGIP1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 19 15 4.07
Lung adenocarcinoma No 13 13 3.32
Lung squamous cell carcinoma No 15 12 6.90
Small cell lung carcinoma No 7 7 10.14
Stomach adenocarcinoma No 7 6 3.73
Head and neck squamous cell carcinoma No 7 6 1.60
Esophageal carcinoma No 7 5 3.42
Breast carcinoma No 4 4 0.35
Glioblastoma multiforme No 3 3 0.79
Prostate adenocarcinoma No 3 2 0.82
Pancreas adenocarcinoma No 2 2 0.93
Renal clear cell carcinoma No 6 2 0.48
Hepatocarcinoma No 1 1 1.11
Uterine corpus endometrioid carcinoma No 2 1 0.43
Lower grade glioma No 1 1 0.59
Serous ovarian adenocarcinoma No 3 1 0.32
Colorectal adenocarcinoma No 1 1 0.44
Non small cell lung carcinoma No 2 0 0.00
Chronic lymphocytic leukemia No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence