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SFPQ mutations in 4 cancer types possibly contribute to the detection of the gene in the PAN-cancer anlaysis:: Lung adenocarcinoma, Bladder carcinoma, Breast carcinoma, Cutaneous melanoma

SFPQ
Ensembl id ENSG00000116560
Mutated samples
Coding Sequence 22 (0.3%)
Protein Affecting 17 (0.3%)
Mode of action Loss of function
Known driver Yes
Cancer type Signals (Biases)
PAN
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all SFPQ gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma Yes 5 5 1.36
Breast carcinoma Yes 4 4 0.35
Lung adenocarcinoma Yes 2 2 0.51
Bladder carcinoma Yes 2 2 2.04
Lung squamous cell carcinoma No 1 1 0.57
Renal clear cell carcinoma No 1 1 0.24
Small cell lung carcinoma No 1 1 1.45
Glioblastoma multiforme No 1 1 0.26
Hepatocarcinoma No 2 0 0.00
Uterine corpus endometrioid carcinoma No 2 0 0.00
Serous ovarian adenocarcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence