Top
IntOGen
SF3B1 × Acute Myeloid Leukemia ×

SF3B1 is detected as a mutational cancer driver in Acute Myeloid Leukemia

SF3B1 reports in Acute Myeloid Leukemia (AML)

Cancer type details
Acute Myeloid Leukemia
Cohorts 9
Samples 661
Mutations 295,755
Driver genes 62
Gene details
SF3B1
Ensembl ID ENSG00000115524
Transcript ID ENST00000335508
Protein ID ENSP00000335321
Cohorts where is driver 2
Mutated samples 13
Mutated samples (%) 1.97
Mutations 20
Mode of action Activating
Known driver True
Method signals per Cohort
Cohort Methods Samples Samples (%)
ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
Observed mutations in tumors
The mutations needle plot shows the distribution of the observed mutations along the protein sequence.
Mutation (GRCh38) Protein Position Samples Samples (%) Consequence