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SF3A3 mutations in 3 cancer types possibly contribute to the detection of the gene in the PAN-cancer anlaysis:: Bladder carcinoma, Lung squamous cell carcinoma, Cutaneous melanoma

SF3A3
Ensembl id ENSG00000183431
Mutated samples
Coding Sequence 22 (0.3%)
Protein Affecting 19 (0.3%)
Mode of action Loss of function
Known driver No
Cancer type Signals (Biases)
PAN
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all SF3A3 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma Yes 6 5 1.36
Bladder carcinoma Yes 2 2 2.04
Lung squamous cell carcinoma Yes 2 2 1.15
Hepatocarcinoma No 2 2 2.22
Prostate adenocarcinoma No 1 1 0.41
Lung adenocarcinoma No 1 1 0.26
Breast carcinoma No 1 1 0.09
Renal clear cell carcinoma No 1 1 0.24
Thyroid carcinoma No 2 1 0.31
Lower grade glioma No 1 1 0.59
Stomach adenocarcinoma No 1 1 0.62
Glioblastoma multiforme No 1 1 0.26
Chronic lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence