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SENP7 has not been detected as a mutational cancer driver

SENP7
Ensembl id ENSG00000138468
Mutated samples
Coding Sequence 81 (1.2%)
Protein Affecting 56 (0.8%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all SENP7 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 18 12 3.25
Lung adenocarcinoma No 9 7 1.79
Breast carcinoma No 6 6 0.52
Stomach adenocarcinoma No 8 6 3.73
Lung squamous cell carcinoma No 6 4 2.30
Colorectal adenocarcinoma No 3 3 1.31
Glioblastoma multiforme No 3 3 0.79
Prostate adenocarcinoma No 2 2 0.82
Hepatocarcinoma No 2 2 2.22
Bladder carcinoma No 4 2 2.04
Uterine corpus endometrioid carcinoma No 2 2 0.87
Head and neck squamous cell carcinoma No 3 2 0.53
Acute myeloid leukemia No 1 1 0.51
Renal clear cell carcinoma No 3 1 0.24
Thyroid carcinoma No 1 1 0.31
Lower grade glioma No 1 1 0.59
Serous ovarian adenocarcinoma No 3 1 0.32
Chronic lymphocytic leukemia No 2 0 0.00
Pylocytic astrocytoma No 2 0 0.00
Small cell lung carcinoma No 1 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence