Top
SENP5 has not been detected as a mutational cancer driver

SENP5
Ensembl id ENSG00000119231
Mutated samples
Coding Sequence 58 (0.9%)
Protein Affecting 34 (0.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all SENP5 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 9 7 1.90
Lung squamous cell carcinoma No 7 5 2.87
Head and neck squamous cell carcinoma No 6 4 1.07
Lung adenocarcinoma No 5 3 0.77
Uterine corpus endometrioid carcinoma No 4 3 1.30
Stomach adenocarcinoma No 5 2 1.24
Small cell lung carcinoma No 2 2 2.90
Bladder carcinoma No 1 1 1.02
Breast carcinoma No 2 1 0.09
Renal clear cell carcinoma No 2 1 0.24
Thyroid carcinoma No 1 1 0.31
Non small cell lung carcinoma No 1 1 3.23
Lower grade glioma No 1 1 0.59
Glioblastoma multiforme No 2 1 0.26
Acute lymphocytic leukemia No 1 1 0.82
Hepatocarcinoma No 5 0 0.00
Medulloblastoma No 1 0 0.00
Colorectal adenocarcinoma No 1 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
Esophageal carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence