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SENP2 has not been detected as a mutational cancer driver

SENP2
Ensembl id ENSG00000163904
Mutated samples
Coding Sequence 40 (0.6%)
Protein Affecting 29 (0.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all SENP2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 16 13 3.52
Lung adenocarcinoma No 3 3 0.77
Lung squamous cell carcinoma No 5 3 1.72
Head and neck squamous cell carcinoma No 3 3 0.80
Uterine corpus endometrioid carcinoma No 2 2 0.87
Breast carcinoma No 1 1 0.09
Chronic lymphocytic leukemia No 2 1 0.34
Stomach adenocarcinoma No 2 1 0.62
Colorectal adenocarcinoma No 1 1 0.44
Esophageal carcinoma No 1 1 0.68
Hepatocarcinoma No 3 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence