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SEMA5B has not been detected as a mutational cancer driver

SEMA5B
Ensembl id ENSG00000082684
Mutated samples
Coding Sequence 125 (1.8%)
Protein Affecting 80 (1.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all SEMA5B gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 36 17 4.61
Head and neck squamous cell carcinoma No 15 9 2.40
Lung adenocarcinoma No 13 8 2.05
Bladder carcinoma No 8 7 7.14
Breast carcinoma No 8 7 0.61
Lung squamous cell carcinoma No 9 6 3.45
Colorectal adenocarcinoma No 7 6 2.62
Stomach adenocarcinoma No 8 5 3.11
Esophageal carcinoma No 4 4 2.74
Pancreas adenocarcinoma No 3 3 1.40
Small cell lung carcinoma No 4 3 4.35
Uterine corpus endometrioid carcinoma No 2 2 0.87
Chronic lymphocytic leukemia No 3 1 0.34
Serous ovarian adenocarcinoma No 2 1 0.32
Glioblastoma multiforme No 2 1 0.26
Diffuse B cell lymphoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence