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SATB2 has not been detected as a mutational cancer driver

SATB2
Ensembl id ENSG00000119042
Mutated samples
Coding Sequence 98 (1.4%)
Protein Affecting 71 (1.0%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all SATB2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma No 17 16 4.09
Cutaneous melanoma No 23 14 3.79
Head and neck squamous cell carcinoma No 11 10 2.67
Lung squamous cell carcinoma No 10 7 4.02
Small cell lung carcinoma No 6 6 8.70
Breast carcinoma No 5 4 0.35
Renal clear cell carcinoma No 4 4 0.96
Bladder carcinoma No 3 3 3.06
Uterine corpus endometrioid carcinoma No 4 3 1.30
Hepatocarcinoma No 2 1 1.11
Multiple myeloma No 1 1 1.45
Colorectal adenocarcinoma No 2 1 0.44
Esophageal carcinoma No 2 1 0.68
Chronic lymphocytic leukemia No 5 0 0.00
Serous ovarian adenocarcinoma No 1 0 0.00
Stomach adenocarcinoma No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence