IntOGen - RXRA gene cancer mutations

RXRA is detected as a mutational cancer driver

RXRA reports

Methods
Mutation distribution

Gene details

RXRA
Ensembl ID ENSG00000186350 Transcript ID ENST00000481739 Protein ID ENSP00000419692
Cancer types where is driver 1 Cohorts where is driver 3 Mutated samples 40 Mutations 248
Mode of action Activating
Known driver False

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence