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RUNX1 has not been detected as a mutational cancer driver in this cancer type

Esophageal carcinoma
Projects 1
146 Samples
Coding sequence mutations (CSMs)
in driver genes 455
in all genes 40925
Protein affecting mutations (PAMs)
in driver genes 368
in all genes 17832
RUNX1
Ensembl id ENSG00000159216
Mutated samples
Coding Sequence 4 (2.7%)
Protein Affecting 4 (2.7%)
Mode of action Loss of function
Known driver Yes
Project Signals
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated Esophageal carcinoma projects in all RUNX1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Project Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Esophagea cancer Dana Farber Cancer Institute obtained from AlexandrovEtAl No 4 4 2.74
The mutations needle plot shows the distribution of the observed RUNX1 cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence Driver classification