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RPF1 has not been detected as a mutational cancer driver

RPF1
Ensembl id ENSG00000117133
Mutated samples
Coding Sequence 23 (0.3%)
Protein Affecting 12 (0.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all RPF1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Head and neck squamous cell carcinoma No 3 3 0.80
Breast carcinoma No 3 2 0.17
Glioblastoma multiforme No 3 2 0.53
Hepatocarcinoma No 1 1 1.11
Renal clear cell carcinoma No 2 1 0.24
Cutaneous melanoma No 2 1 0.27
Uterine corpus endometrioid carcinoma No 1 1 0.43
Small cell lung carcinoma No 1 1 1.45
Lung squamous cell carcinoma No 1 0 0.00
Thyroid carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 2 0 0.00
Stomach adenocarcinoma No 3 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence