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RORC has not been detected as a mutational cancer driver

RORC
Ensembl id ENSG00000143365
Mutated samples
Coding Sequence 89 (1.3%)
Protein Affecting 31 (0.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all RORC gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 31 10 2.71
Breast carcinoma No 6 3 0.26
Uterine corpus endometrioid carcinoma No 7 3 1.30
Stomach adenocarcinoma No 4 3 1.86
Glioblastoma multiforme No 5 3 0.79
Bladder carcinoma No 3 2 2.04
Lung squamous cell carcinoma No 5 2 1.15
Neuroblastoma No 2 2 0.95
Lung adenocarcinoma No 5 1 0.26
Serous ovarian adenocarcinoma No 2 1 0.32
Head and neck squamous cell carcinoma No 9 1 0.27
Hepatocarcinoma No 3 0 0.00
Renal clear cell carcinoma No 1 0 0.00
Multiple myeloma No 2 0 0.00
Lower grade glioma No 2 0 0.00
Small cell lung carcinoma No 1 0 0.00
Esophageal carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence