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RNF144A has not been detected as a mutational cancer driver

RNF144A
Ensembl id ENSG00000151692
Mutated samples
Coding Sequence 41 (0.6%)
Protein Affecting 25 (0.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all RNF144A gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung squamous cell carcinoma No 7 7 4.02
Lung adenocarcinoma No 5 4 1.02
Renal clear cell carcinoma No 2 2 0.48
Cutaneous melanoma No 4 2 0.54
Stomach adenocarcinoma No 2 2 1.24
Bladder carcinoma No 1 1 1.02
Breast carcinoma No 1 1 0.09
Uterine corpus endometrioid carcinoma No 2 1 0.43
Lower grade glioma No 1 1 0.59
Small cell lung carcinoma No 1 1 1.45
Head and neck squamous cell carcinoma No 1 1 0.27
Diffuse B cell lymphoma No 1 1 4.35
Glioblastoma multiforme No 1 1 0.26
Prostate adenocarcinoma No 1 0 0.00
Hepatocarcinoma No 1 0 0.00
Medulloblastoma No 1 0 0.00
Chronic lymphocytic leukemia No 6 0 0.00
Multiple myeloma No 1 0 0.00
Serous ovarian adenocarcinoma No 1 0 0.00
Esophageal carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence