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RGPD4 has not been detected as a mutational cancer driver

RGPD4
Ensembl id ENSG00000196862
Mutated samples
Coding Sequence 121 (1.8%)
Protein Affecting 99 (1.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all RGPD4 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 67 56 15.18
Lung adenocarcinoma No 18 15 3.84
Head and neck squamous cell carcinoma No 8 7 1.87
Breast carcinoma No 8 6 0.52
Uterine corpus endometrioid carcinoma No 5 4 1.74
Glioblastoma multiforme No 5 4 1.06
Bladder carcinoma No 3 3 3.06
Renal clear cell carcinoma No 2 1 0.24
Thyroid carcinoma No 1 1 0.31
Lower grade glioma No 1 1 0.59
Stomach adenocarcinoma No 1 1 0.62
Prostate adenocarcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence