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RETNLB has not been detected as a mutational cancer driver

RETNLB
Ensembl id ENSG00000163515
Mutated samples
Coding Sequence 40 (0.6%)
Protein Affecting 18 (0.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all RETNLB gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 26 9 2.44
Lung squamous cell carcinoma No 3 2 1.15
Small cell lung carcinoma No 2 2 2.90
Lung adenocarcinoma No 1 1 0.26
Breast carcinoma No 2 1 0.09
Non small cell lung carcinoma No 1 1 3.23
Glioblastoma multiforme No 1 1 0.26
Esophageal carcinoma No 1 1 0.68
Uterine corpus endometrioid carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Lower grade glioma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence