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RET has not been detected as a mutational cancer driver in this cancer type

Lung adenocarcinoma
Projects 2
391 Samples
Coding sequence mutations (CSMs)
in driver genes 1564
in all genes 112729
Protein affecting mutations (PAMs)
in driver genes 1381
in all genes 61402
RET
Ensembl id ENSG00000165731
Mutated samples
Coding Sequence 12 (3.1%)
Protein Affecting 11 (2.8%)
Mode of action Unclassified
Known driver No
Project Signals
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated Lung adenocarcinoma projects in all RET gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Project Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma TCGA No 9 8 2.05
Lung adenocarcinoma Washington University No 3 3 0.77
The mutations needle plot shows the distribution of the observed RET cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence Driver classification