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REN has not been detected as a mutational cancer driver

REN
Ensembl id ENSG00000143839
Mutated samples
Coding Sequence 49 (0.7%)
Protein Affecting 34 (0.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all REN gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 15 11 2.98
Glioblastoma multiforme No 6 4 1.06
Bladder carcinoma No 3 3 3.06
Head and neck squamous cell carcinoma No 5 3 0.80
Lung adenocarcinoma No 4 2 0.51
Breast carcinoma No 2 2 0.17
Stomach adenocarcinoma No 3 2 1.24
Colorectal adenocarcinoma No 2 2 0.87
Pancreas adenocarcinoma No 1 1 0.47
Renal clear cell carcinoma No 1 1 0.24
Uterine corpus endometrioid carcinoma No 1 1 0.43
Non small cell lung carcinoma No 1 1 3.23
Esophageal carcinoma No 3 1 0.68
Hepatocarcinoma No 1 0 0.00
Lower grade glioma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence