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REG1B has not been detected as a mutational cancer driver

REG1B
Ensembl id ENSG00000172023
Mutated samples
Coding Sequence 70 (1.0%)
Protein Affecting 55 (0.8%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all REG1B gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma No 15 14 3.58
Lung squamous cell carcinoma No 11 11 6.32
Cutaneous melanoma No 19 9 2.44
Head and neck squamous cell carcinoma No 6 6 1.60
Small cell lung carcinoma No 5 5 7.25
Esophageal carcinoma No 4 3 2.05
Breast carcinoma No 2 2 0.17
Glioblastoma multiforme No 2 2 0.53
Renal clear cell carcinoma No 1 1 0.24
Stomach adenocarcinoma No 1 1 0.62
Colorectal adenocarcinoma No 1 1 0.44
Hepatocarcinoma No 1 0 0.00
Bladder carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence