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RBM5 mutations in 5 cancer types possibly contribute to the detection of the gene in the PAN-cancer anlaysis:: Lung adenocarcinoma, Bladder carcinoma, Breast carcinoma, Uterine corpus endometrioid carcinoma, Stomach adenocarcinoma

RBM5
Ensembl id ENSG00000003756
Mutated samples
Coding Sequence 39 (0.6%)
Protein Affecting 31 (0.5%)
Mode of action Loss of function
Known driver No
Cancer type Signals (Biases)
PAN
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all RBM5 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma Yes 3 3 0.77
Breast carcinoma Yes 3 3 0.26
Bladder carcinoma Yes 2 2 2.04
Uterine corpus endometrioid carcinoma Yes 3 2 0.87
Stomach adenocarcinoma Yes 3 2 1.24
Cutaneous melanoma No 13 9 2.44
Head and neck squamous cell carcinoma No 5 5 1.33
Prostate adenocarcinoma No 1 1 0.41
Lung squamous cell carcinoma No 1 1 0.57
Neuroblastoma No 1 1 0.48
Colorectal adenocarcinoma No 1 1 0.44
Esophageal carcinoma No 1 1 0.68
Hepatocarcinoma No 1 0 0.00
Non small cell lung carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence