IntOGen - RBM39 gene cancer mutations

RBM39 is detected as a mutational cancer driver

RBM39 reports

Methods
Mutation distribution

Gene details

RBM39
Ensembl ID ENSG00000131051 Transcript ID ENST00000253363 Protein ID ENSP00000253363
Cancer types where is driver 1 Cohorts where is driver 1 Mutated samples 8 Mutations 185
Mode of action Activating
Known driver False

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence