Top
RAVER2 has not been detected as a mutational cancer driver

RAVER2
Ensembl id ENSG00000162437
Mutated samples
Coding Sequence 46 (0.7%)
Protein Affecting 22 (0.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all RAVER2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 14 8 2.17
Head and neck squamous cell carcinoma No 7 4 1.07
Bladder carcinoma No 4 2 2.04
Lung squamous cell carcinoma No 2 2 1.15
Lung adenocarcinoma No 4 1 0.26
Breast carcinoma No 5 1 0.09
Non small cell lung carcinoma No 1 1 3.23
Lower grade glioma No 1 1 0.59
Stomach adenocarcinoma No 1 1 0.62
Small cell lung carcinoma No 1 1 1.45
Prostate adenocarcinoma No 1 0 0.00
Medulloblastoma No 1 0 0.00
Uterine corpus endometrioid carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Glioblastoma multiforme No 1 0 0.00
Esophageal carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence