Top
RASAL2 has not been detected as a mutational cancer driver

RASAL2
Ensembl id ENSG00000075391
Mutated samples
Coding Sequence 100 (1.5%)
Protein Affecting 76 (1.1%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all RASAL2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 24 19 5.15
Breast carcinoma No 10 10 0.87
Stomach adenocarcinoma No 10 8 4.97
Lung adenocarcinoma No 8 7 1.79
Lung squamous cell carcinoma No 10 7 4.02
Uterine corpus endometrioid carcinoma No 6 5 2.17
Head and neck squamous cell carcinoma No 7 5 1.33
Colorectal adenocarcinoma No 5 4 1.75
Bladder carcinoma No 2 2 2.04
Neuroblastoma No 2 2 0.95
Serous ovarian adenocarcinoma No 2 2 0.63
Small cell lung carcinoma No 2 2 2.90
Prostate adenocarcinoma No 2 1 0.41
Hepatocarcinoma No 2 1 1.11
Glioblastoma multiforme No 2 1 0.26
Pancreas adenocarcinoma No 1 0 0.00
Thyroid carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Pylocytic astrocytoma No 1 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
Esophageal carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence