Top
RANBP2 has not been detected as a mutational cancer driver

RANBP2
Ensembl id ENSG00000153201
Mutated samples
Coding Sequence 156 (2.3%)
Protein Affecting 119 (1.8%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all RANBP2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 39 30 8.13
Stomach adenocarcinoma No 15 12 7.45
Lung adenocarcinoma No 15 11 2.81
Lung squamous cell carcinoma No 13 11 6.32
Breast carcinoma No 10 8 0.70
Renal clear cell carcinoma No 9 8 1.92
Head and neck squamous cell carcinoma No 11 7 1.87
Bladder carcinoma No 7 6 6.12
Uterine corpus endometrioid carcinoma No 8 6 2.61
Small cell lung carcinoma No 5 5 7.25
Colorectal adenocarcinoma No 6 5 2.18
Esophageal carcinoma No 6 4 2.74
Hepatocarcinoma No 2 1 1.11
Pancreas adenocarcinoma No 1 1 0.47
Thyroid carcinoma No 2 1 0.31
Multiple myeloma No 2 1 1.45
Lower grade glioma No 1 1 0.59
Glioblastoma multiforme No 1 1 0.26
Prostate adenocarcinoma No 2 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence