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RAB28 has not been detected as a mutational cancer driver

RAB28
Ensembl id ENSG00000157869
Mutated samples
Coding Sequence 19 (0.3%)
Protein Affecting 11 (0.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all RAB28 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma No 2 2 0.51
Serous ovarian adenocarcinoma No 2 2 0.63
Glioblastoma multiforme No 2 2 0.53
Breast carcinoma No 1 1 0.09
Cutaneous melanoma No 2 1 0.27
Uterine corpus endometrioid carcinoma No 3 1 0.43
Stomach adenocarcinoma No 1 1 0.62
Small cell lung carcinoma No 1 1 1.45
Lung squamous cell carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 2 0 0.00
Pylocytic astrocytoma No 1 0 0.00
Colorectal adenocarcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence