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PTGER3 has not been detected as a mutational cancer driver

PTGER3
Ensembl id ENSG00000050628
Mutated samples
Coding Sequence 72 (1.1%)
Protein Affecting 33 (0.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all PTGER3 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 21 7 1.90
Stomach adenocarcinoma No 8 5 3.11
Lung adenocarcinoma No 4 4 1.02
Lung squamous cell carcinoma No 5 4 2.30
Breast carcinoma No 4 3 0.26
Colorectal adenocarcinoma No 2 2 0.87
Head and neck squamous cell carcinoma No 2 2 0.53
Esophageal carcinoma No 5 2 1.37
Pancreas adenocarcinoma No 1 1 0.47
Non small cell lung carcinoma No 1 1 3.23
Small cell lung carcinoma No 1 1 1.45
Diffuse B cell lymphoma No 2 1 4.35
Hepatocarcinoma No 6 0 0.00
Uterine corpus endometrioid carcinoma No 2 0 0.00
Chronic lymphocytic leukemia No 6 0 0.00
Pylocytic astrocytoma No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence