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PTEN mutations in 1 Thyroid carcinoma project possibly contribute to the detection of the gene in the PAN-cancer anlaysis:

Thyroid carcinoma
Projects 1
322 Samples
Coding sequence mutations (CSMs)
in driver genes 316
in all genes 10749
Protein affecting mutations (PAMs)
in driver genes 305
in all genes 5121
PTEN
Ensembl id ENSG00000171862
Mutated samples
Coding Sequence 2 (0.6%)
Protein Affecting 2 (0.6%)
Mode of action Loss of function
Known driver Yes
Project Signals
PAN
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated Thyroid carcinoma projects in all PTEN gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Project Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Thyroid Cancer TCGA obtained from Synapse Yes 2 2 0.62
The mutations needle plot shows the distribution of the observed PTEN cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence Driver classification