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PTEN is detected as a mutational cancer driver in Stomach Adenocarcinoma

PTEN reports in Stomach Adenocarcinoma (STAD)

Cancer type details
Stomach Adenocarcinoma
Cohorts 6
Samples 858
Mutations 6,723,174
Driver genes 75
Gene details
PTEN
Ensembl ID ENSG00000171862
Transcript ID ENST00000371953
Protein ID ENSP00000361021
Cohorts where is driver 1
Mutated samples 14
Mutated samples (%) 1.63
Mutations 27
Mode of action Loss of function
Known driver True
Method signals per Cohort
Cohort Methods Samples Samples (%)
ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
Observed mutations in tumors
The mutations needle plot shows the distribution of the observed mutations along the protein sequence.
Mutation (GRCh38) Protein Position Samples Samples (%) Consequence