PTEN mutations in 1 Serous ovarian adenocarcinoma project possibly contribute to the detection of the gene in the PAN-cancer anlaysis:

Serous ovarian adenocarcinoma
Projects 1
316 Samples
Coding sequence mutations (CSMs)
in driver genes 599
in all genes 26845
Protein affecting mutations (PAMs)
in driver genes 544
in all genes 14718
Ensembl id ENSG00000171862
Mutated samples
Coding Sequence 2 (0.6%)
Protein Affecting 2 (0.6%)
Mode of action Loss of function
Known driver Yes
Project Signals
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated Serous ovarian adenocarcinoma projects in all PTEN gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Project Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Ovarian serous cystadenocarcinoma TCGA Yes 2 2 0.63
The mutations needle plot shows the distribution of the observed PTEN cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence Driver classification