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PSMD1 has not been detected as a mutational cancer driver

PSMD1
Ensembl id ENSG00000173692
Mutated samples
Coding Sequence 68 (1.0%)
Protein Affecting 30 (0.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all PSMD1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Breast carcinoma No 8 5 0.44
Cutaneous melanoma No 12 5 1.36
Bladder carcinoma No 6 4 4.08
Lung squamous cell carcinoma No 6 4 2.30
Lung adenocarcinoma No 4 2 0.51
Uterine corpus endometrioid carcinoma No 2 2 0.87
Small cell lung carcinoma No 3 2 2.90
Colorectal adenocarcinoma No 4 2 0.87
Neuroblastoma No 2 1 0.48
Serous ovarian adenocarcinoma No 1 1 0.32
Stomach adenocarcinoma No 3 1 0.62
Head and neck squamous cell carcinoma No 4 1 0.27
Prostate adenocarcinoma No 1 0 0.00
Hepatocarcinoma No 2 0 0.00
Renal clear cell carcinoma No 2 0 0.00
Thyroid carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Multiple myeloma No 1 0 0.00
Lower grade glioma No 1 0 0.00
Pylocytic astrocytoma No 1 0 0.00
Esophageal carcinoma No 3 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence