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PSMB4 has not been detected as a mutational cancer driver

PSMB4
Ensembl id ENSG00000159377
Mutated samples
Coding Sequence 45 (0.7%)
Protein Affecting 12 (0.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all PSMB4 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung squamous cell carcinoma No 4 2 1.15
Cutaneous melanoma No 8 2 0.54
Stomach adenocarcinoma No 5 2 1.24
Head and neck squamous cell carcinoma No 3 2 0.53
Lung adenocarcinoma No 2 1 0.26
Renal clear cell carcinoma No 2 1 0.24
Uterine corpus endometrioid carcinoma No 2 1 0.43
Serous ovarian adenocarcinoma No 3 1 0.32
Prostate adenocarcinoma No 1 0 0.00
Hepatocarcinoma No 1 0 0.00
Bladder carcinoma No 2 0 0.00
Breast carcinoma No 5 0 0.00
Medulloblastoma No 1 0 0.00
Thyroid carcinoma No 1 0 0.00
Non small cell lung carcinoma No 2 0 0.00
Multiple myeloma No 2 0 0.00
Colorectal adenocarcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence