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PRPS2 has not been detected as a mutational cancer driver

PRPS2
Ensembl id ENSG00000101911
Mutated samples
Coding Sequence 33 (0.5%)
Protein Affecting 19 (0.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all PRPS2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 7 4 1.08
Uterine corpus endometrioid carcinoma No 4 3 1.30
Lung squamous cell carcinoma No 2 2 1.15
Renal clear cell carcinoma No 2 2 0.48
Glioblastoma multiforme No 2 2 0.53
Breast carcinoma No 2 1 0.09
Neuroblastoma No 1 1 0.48
Lower grade glioma No 1 1 0.59
Stomach adenocarcinoma No 1 1 0.62
Colorectal adenocarcinoma No 2 1 0.44
Head and neck squamous cell carcinoma No 1 1 0.27
Prostate adenocarcinoma No 1 0 0.00
Lung adenocarcinoma No 1 0 0.00
Medulloblastoma No 1 0 0.00
Thyroid carcinoma No 1 0 0.00
Non small cell lung carcinoma No 2 0 0.00
Multiple myeloma No 1 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence