Top
PRPF38A has not been detected as a mutational cancer driver

PRPF38A
Ensembl id ENSG00000134748
Mutated samples
Coding Sequence 20 (0.3%)
Protein Affecting 7 (0.1%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all PRPF38A gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Breast carcinoma No 3 2 0.17
Lung adenocarcinoma No 3 1 0.26
Cutaneous melanoma No 3 1 0.27
Stomach adenocarcinoma No 3 1 0.62
Colorectal adenocarcinoma No 1 1 0.44
Glioblastoma multiforme No 1 1 0.26
Hepatocarcinoma No 1 0 0.00
Bladder carcinoma No 1 0 0.00
Lung squamous cell carcinoma No 2 0 0.00
Renal clear cell carcinoma No 1 0 0.00
Uterine corpus endometrioid carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence