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PRKAA2 has not been detected as a mutational cancer driver

PRKAA2
Ensembl id ENSG00000162409
Mutated samples
Coding Sequence 86 (1.3%)
Protein Affecting 64 (0.9%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all PRKAA2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 44 31 8.40
Breast carcinoma No 7 6 0.52
Lung squamous cell carcinoma No 5 5 2.87
Colorectal adenocarcinoma No 4 4 1.75
Bladder carcinoma No 3 3 3.06
Small cell lung carcinoma No 3 3 4.35
Head and neck squamous cell carcinoma No 4 3 0.80
Esophageal carcinoma No 5 3 2.05
Serous ovarian adenocarcinoma No 2 2 0.63
Prostate adenocarcinoma No 1 1 0.41
Acute myeloid leukemia No 1 1 0.51
Neuroblastoma No 2 1 0.48
Stomach adenocarcinoma No 1 1 0.62
Lung adenocarcinoma No 1 0 0.00
Hepatocarcinoma No 1 0 0.00
Medulloblastoma No 1 0 0.00
Lower grade glioma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence