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PRAMEF2 has not been detected as a mutational cancer driver

PRAMEF2
Ensembl id ENSG00000120952
Mutated samples
Coding Sequence 83 (1.2%)
Protein Affecting 59 (0.9%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all PRAMEF2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 37 23 6.23
Lung adenocarcinoma No 7 7 1.79
Head and neck squamous cell carcinoma No 8 6 1.60
Breast carcinoma No 5 4 0.35
Lung squamous cell carcinoma No 8 4 2.30
Prostate adenocarcinoma No 2 2 0.82
Acute myeloid leukemia No 2 2 1.02
Chronic lymphocytic leukemia No 2 2 0.69
Stomach adenocarcinoma No 2 2 1.24
Glioblastoma multiforme No 4 2 0.53
Bladder carcinoma No 1 1 1.02
Renal clear cell carcinoma No 1 1 0.24
Uterine corpus endometrioid carcinoma No 1 1 0.43
Lower grade glioma No 1 1 0.59
Small cell lung carcinoma No 2 1 1.45
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence