PRAMEF11 has not been detected as a mutational cancer driver

Ensembl id ENSG00000204513
Mutated samples
Coding Sequence 78 (1.1%)
Protein Affecting 55 (0.8%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all PRAMEF11 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 45 29 7.86
Breast carcinoma No 6 6 0.52
Head and neck squamous cell carcinoma No 6 6 1.60
Lung adenocarcinoma No 4 4 1.02
Lower grade glioma No 4 3 1.78
Esophageal carcinoma No 4 3 2.05
Prostate adenocarcinoma No 4 2 0.82
Bladder carcinoma No 2 1 1.02
Glioblastoma multiforme No 1 1 0.26
Acute myeloid leukemia No 1 0 0.00
Neuroblastoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence