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PPP2R2C has not been detected as a mutational cancer driver

PPP2R2C
Ensembl id ENSG00000074211
Mutated samples
Coding Sequence 54 (0.8%)
Protein Affecting 24 (0.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all PPP2R2C gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 18 9 2.44
Stomach adenocarcinoma No 4 3 1.86
Colorectal adenocarcinoma No 5 3 1.31
Lung squamous cell carcinoma No 2 2 1.15
Prostate adenocarcinoma No 1 1 0.41
Lung adenocarcinoma No 5 1 0.26
Bladder carcinoma No 3 1 1.02
Renal clear cell carcinoma No 2 1 0.24
Chronic lymphocytic leukemia No 6 1 0.34
Lower grade glioma No 1 1 0.59
Esophageal carcinoma No 2 1 0.68
Uterine corpus endometrioid carcinoma No 1 0 0.00
Serous ovarian adenocarcinoma No 2 0 0.00
Pylocytic astrocytoma No 1 0 0.00
Glioblastoma multiforme No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence