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PPM1B has not been detected as a mutational cancer driver

PPM1B
Ensembl id ENSG00000138032
Mutated samples
Coding Sequence 37 (0.5%)
Protein Affecting 28 (0.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all PPM1B gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 10 8 2.17
Lung adenocarcinoma No 4 3 0.77
Breast carcinoma No 5 3 0.26
Lung squamous cell carcinoma No 3 3 1.72
Bladder carcinoma No 2 2 2.04
Renal clear cell carcinoma No 4 2 0.48
Non small cell lung carcinoma No 2 2 6.45
Stomach adenocarcinoma No 2 2 1.24
Lower grade glioma No 1 1 0.59
Colorectal adenocarcinoma No 1 1 0.44
Glioblastoma multiforme No 1 1 0.26
Diffuse B cell lymphoma No 1 0 0.00
Esophageal carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence