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PPARG has not been detected as a mutational cancer driver

PPARG
Ensembl id ENSG00000132170
Mutated samples
Coding Sequence 44 (0.6%)
Protein Affecting 27 (0.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all PPARG gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 15 11 2.98
Lung adenocarcinoma No 6 3 0.77
Stomach adenocarcinoma No 4 3 1.86
Bladder carcinoma No 2 2 2.04
Breast carcinoma No 3 2 0.17
Uterine corpus endometrioid carcinoma No 2 2 0.87
Prostate adenocarcinoma No 1 1 0.41
Renal clear cell carcinoma No 2 1 0.24
Lower grade glioma No 2 1 0.59
Glioblastoma multiforme No 1 1 0.26
Medulloblastoma No 1 0 0.00
Chronic lymphocytic leukemia No 3 0 0.00
Serous ovarian adenocarcinoma No 1 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence