Top
PLXNB3 has not been detected as a mutational cancer driver

PLXNB3
Ensembl id ENSG00000198753
Mutated samples
Coding Sequence 91 (1.3%)
Protein Affecting 47 (0.7%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all PLXNB3 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 17 9 2.44
Uterine corpus endometrioid carcinoma No 8 5 2.17
Stomach adenocarcinoma No 7 5 3.11
Head and neck squamous cell carcinoma No 7 5 1.33
Bladder carcinoma No 6 4 4.08
Lung squamous cell carcinoma No 4 4 2.30
Lung adenocarcinoma No 11 3 0.77
Breast carcinoma No 8 3 0.26
Thyroid carcinoma No 3 2 0.62
Small cell lung carcinoma No 2 2 2.90
Medulloblastoma No 1 1 0.48
Non small cell lung carcinoma No 1 1 3.23
Chronic lymphocytic leukemia No 2 1 0.34
Colorectal adenocarcinoma No 1 1 0.44
Glioblastoma multiforme No 6 1 0.26
Prostate adenocarcinoma No 2 0 0.00
Pancreas adenocarcinoma No 1 0 0.00
Renal clear cell carcinoma No 2 0 0.00
Lower grade glioma No 1 0 0.00
Serous ovarian adenocarcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence