Top
PKP1 has not been detected as a mutational cancer driver

PKP1
Ensembl id ENSG00000081277
Mutated samples
Coding Sequence 41 (0.6%)
Protein Affecting 25 (0.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all PKP1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 19 10 2.71
Lung adenocarcinoma No 4 4 1.02
Uterine corpus endometrioid carcinoma No 4 3 1.30
Serous ovarian adenocarcinoma No 3 3 0.95
Breast carcinoma No 3 2 0.17
Stomach adenocarcinoma No 2 2 1.24
Hepatocarcinoma No 2 1 1.11
Chronic lymphocytic leukemia No 1 0 0.00
Lower grade glioma No 1 0 0.00
Colorectal adenocarcinoma No 1 0 0.00
Glioblastoma multiforme No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence