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PKD2L2 has not been detected as a mutational cancer driver

PKD2L2
Ensembl id ENSG00000078795
Mutated samples
Coding Sequence 64 (0.9%)
Protein Affecting 30 (0.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all PKD2L2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 16 7 1.90
Lung adenocarcinoma No 4 4 1.02
Uterine corpus endometrioid carcinoma No 6 4 1.74
Breast carcinoma No 4 3 0.26
Lung squamous cell carcinoma No 4 3 1.72
Renal clear cell carcinoma No 6 2 0.48
Stomach adenocarcinoma No 7 2 1.24
Head and neck squamous cell carcinoma No 3 2 0.53
Neuroblastoma No 1 1 0.48
Colorectal adenocarcinoma No 2 1 0.44
Glioblastoma multiforme No 2 1 0.26
Prostate adenocarcinoma No 1 0 0.00
Bladder carcinoma No 2 0 0.00
Medulloblastoma No 1 0 0.00
Chronic lymphocytic leukemia No 2 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
Esophageal carcinoma No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence